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Neutralising antibodies to sclerostin (Scl-Ab) have shown significant potential to induce bone formation and decrease bone resorption, increase strength and substantially reduce fracture risk in animal studies and clinical trials. Mechanical loading negatively regulates sclerostin expression, and sclerostin has been shown to induce RANKL synthesis in osteocytes.
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Cells were harvested by centrifuging at 1500×g for 5 min at RT, and washed with sterile double-distilled water. Cells were resuspended in water to an OD 600 = 120 and 25 ml of this suspension was added into twelve 250 ml baffled flasks prefilled with 25 …
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Conclusion: The phosphorylation of Thr308 is a more reliable biomarker for the protein kinase activity of Akt in tumour samples than Ser473. Any evaluation of the link between Akt phosphorylation or activity in tumour samples and the prediction or prognosis of disease should, therefore, focus on measuring the phosphorylation of Akt on Thr308 and/or at least one downstream …
Antimicrobial peptides (AMPs) are the first line of host immune defense against pathogens. Among AMPs from the honeybee Apis mellifera, abaecin is a major broad-spectrum antibacterial proline-enriched cationic peptide. For heterologous expression of abaecin in Pichia pastoris, we designed an ORF with HisTag, and the codon usage was optimized.
4. Brick Machine (Model JJ 1500 BMM) JJ 1500 BMM is hydraulically operated, automatic, PLC controlled, self diagnosing type, having digital display. Computer connection can be fitted if required. The machine develops approx. 35 tonnes of …
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Int J Obes 2015; 39: 1494–1500. ... Monteiro PA, Chen KY, Lira FS, Saraiva BTC, Antunes BMM, Campos EZ et al. Concurrent and aerobic exercise training promote similar benefits in body ...
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Deeks JJ, Macaskill P, Irwig L. The performance of tests of publication bias and other sample size effects in systematic reviews of diagnostic test accuracy was assessed. J Clin Epidemiol 2005; 58:882-93. . 10.1016/j.jclinepi.2005.01.016 [Google Scholar]
CYP-GUIDES (Cytochrome Psychotropic Genotyping Under Investigation for Decision Support) was a Randomized Controlled Trial comparing 2 outcomes in hospitalized patients with major depressive disorder treated according to the patient's CYP2D6 genotype and functional status versus standard psychotropic therapy. The primary outcome was hospital Length of Stay (LOS) and the …
BMM, BQ, BPQ 1145–2650 1500–2400 1959 Polypodium castaneum Maxon ex Tejero BQ, BMM 1700–1800 1700–1800 1750 Polypodium colpodes Kunze BG, BQ, BPQ, BTC, BTP, BTS 240–2100 900–1500 1290 Polypodium conterminans Liebm BMM, BQ, BPQ 900–3000 1500–2400 1981 Polypodium eatonii Baker BMM, BPQ, BG, BTC 1200–1560
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Equal numbers of BMM cells from and male mice were cultured with M-CSF and with or without RANKL (3, 10, or 30 ng/mL) for 4 days to determine whether there were differences in osteoclastogenesis in vitro between LysM-Cre Runx1 fl/fl and Runx1 fl/+ mice . For both genotypes, BMMs formed more osteoclasts than did male cells for all ...
Purpose. To develop a novel pulse sequence for free‐breathing, multislice, native myocardial T 1 mapping.. Methods. The slice‐interleaved T 1 (STONE) sequence consists of multiple sets of single‐shot images of different slices, acquired after a single nonselective inversion pulse. Each slice is only selectively excited once after each inversion pulse to allow sampling of the unperturbed ...
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It's better to store it in -20C freezer. 0.2ng/ml EGF can promote the proliferation of limbal stem cells. Reason for Rating: 10 ng/ml to induce migration of breast cancer cells. Growth of MDA--231 spheroids in serum-free condition in the absence (A) or presence …
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